https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Changes in cell cycle and up-regulation of neuronal markers during SH-SY5Y neurodifferentiation by retinoic acid are mediated by reactive species production and oxidative stress https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33343 Wed 17 Nov 2021 16:32:09 AEDT ]]> Complement peptide C3a promotes astrocyte survival in response to ischemic stress https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23930 Wed 17 Nov 2021 16:31:15 AEDT ]]> From Hair to the Brain: The Short-Term Therapeutic Potential of Human Hair Follicle-Derived Stem Cells and Their Conditioned Medium in a Rat Model of Stroke https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52454 Wed 11 Oct 2023 15:03:16 AEDT ]]> NRF2 mediates neuroblastoma proliferation and resistance to retinoic acid cytotoxicity in a model of in vitro neuronal differentiation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26167 Wed 09 Feb 2022 15:57:27 AEDT ]]> Increased neuronal differentiation of neural progenitor cells derived from phosphovimentin-deficient mice https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33582 SA/SA) leads to cytokinetic failures in fibroblasts and lens epithelial cells, resulting in chromosomal instability and increased expression of cell senescence markers. In this study, we investigated morphology, proliferative capacity, and motility of VIMSA/SA astrocytes, and their effect on the differentiation of neural stem/progenitor cells. VIMSA/SA astrocytes expressed less vimentin and more GFAP but showed a well-developed intermediate filament network, exhibited normal cell morphology, proliferation, and motility in an in vitro wound closing assay. Interestingly, we found a two- to fourfold increased neuronal differentiation of VIMSA/SA neurosphere cells, both in a standard 2D and in Bioactive3D cell culture systems, and determined that this effect was neurosphere cell autonomous and not dependent on cocultured astrocytes. Using BrdU in vivo labeling to assess neural stem/progenitor cell proliferation and differentiation in the hippocampus of adult mice, one of the two major adult neurogenic regions, we found a modest increase (by 8%) in the fraction of newly born and surviving neurons. Thus, mutation of the serine sites phosphorylated in vimentin during mitosis alters intermediate filament protein expression but has no effect on astrocyte morphology or proliferation, and leads to increased neuronal differentiation of neural progenitor cells.]]> Tue 03 Sep 2019 17:59:31 AEST ]]> Post-transcriptional trafficking and regulation of neuronal gene expression https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18237 Sat 24 Mar 2018 08:04:53 AEDT ]]>